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Research Assistant or Postdoctoral Research Scientist

Closing Date: 2017-09-20

Institution: Babraham Institute
Closing Date: 2017-09-20
Location: Cambridge, United Kingdom
Salary: £25,795 - £34,166 per annum
Term: until 31 May 2020

Research Assistant or Postdoctoral Research Scientist

Lymphocyte Signalling

The Babraham Institute is a charity which is world renowned for its research in life sciences to enhance lives and improve wellbeing.
 
The Linterman Laboratory are seeking an enthusiastic and motivated Research Assistant or Postdoctoral Research Scientist to participate in a European Research Council (ERC) funded research programme.
 
The programme aims to investigate how the immune system responds to vaccination, and determine how to improve the response in cases where there is an unmet clinical need. The successful applicant will work as part of our team to move our research forward.
 
The position will suit someone who has previous laboratory experience, ideally with familiarity in one or more of the following techniques:

  • Flow cytometry
  • Cell culture
  • Molecular Biology
  • Human blood sample processing
  • Confocal microscopy

 Funding for this position is available up to 31st May 2020, with the possibility for extension after this date.
 
Our laboratory comprises a fun, interactive and international group of scientists who is embedded within the Lymphocyte Signalling and Development Programme at the Babraham Institute. More information can be found at http://www.babraham.ac.uk/our-research/lymphocyte/michelle-linterman
 
Potential candidates are encouraged to contact Michelle Linterman (michelle.linterman@babraham.ac.uk) to discuss the role in more detail.

Starting salary is £25,795 per annum to £34,166 per annum (depending on experience)
 
Further information about the Institute can be found on our website. Application forms and further details are available electronically (www.babraham.ac.uk), or e-mail:  HR@babraham.ac.uk
 
Full details of the position can be found here
 
On applying please quote reference ML-RA-PRS
 
Closing date for completed applications is Wednesday 20th September 2017.
 
NO AGENCIES PLEASE
 
The Babraham Institute is a user of the disability symbol and is positive about disabled people.
 
The Babraham Institute receives strategic funding from the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.

Research Assistant in Molecular Immunology

Closing Date: 2017-09-08

Institution: University of Oxford
Closing Date: 2017-09-08
Location: Oxford, United Kingdom
Salary: £27,629 to £32,958
Term: 2 years
Keywords: Research

Research Assistant in Molecular Immunology

Department of Paediatrics, University of Oxford

A new 2-year research assistant position is available for a highly motivated Research Assistant in the Developmental Immunology research group of Professor Georg Holländer based at Oxford University’s Weatherall Institute of Molecular Medicine (WIMM).

The Research Assistant will work with studies involving molecular methods of genome and transcriptome-wide analyses, flow cytometry and cell sorting, functional cellular assays and other methods. The work will also comprise the design and generation of novel models to study thymus biology.

You will hold a degree or equivalent in molecular biology, molecular immunology, cell biology or any other area of biological sciences relevant to the laboratory’s research focus. Experience with Next Generation Sequencing, epigenomic analyses and bioinformatics are advantageous. The successful applicant will have access to a range of state-of-the-art facilities including The Wolfson Imaging Laboratory. The research group has strong collaborations with the MRC Functional Genomics Unit in Oxford and several internationally recognised laboratories both within the UK and abroad.

The WIMM, with its outstanding core facilities, fosters research in molecular and cell biology with application to the study of human disease. The project will focus on the cellular and molecular networks that control the differentiation and function of thymic epithelial cells. Using novel in vivo models, the programme seeks in particular to determine the stromal mechanisms dictating T cell maturation and central tolerance induction.

Informal enquiries can be made to: georg.hollander@paediatrics.ox.ac.uk.

The closing date for applications is 12.00 noon on 8 September 2017.

Postdoctoral Research Scientist

Closing Date: 2017-09-30

Institution: Beatson Institute for Cancer Research
Closing Date: 2017-09-30
Location: Glasgow, United Kingdom
Salary: £30,000 to £39,800
Term: 3 years
Keywords: Research

Postdoctoral Research Scientist: Regulation of γδ T cell phenotype and trafficking in mammary tumour metastasis

Beatson Institute for Cancer Research

Initial 3 year fixed term contract (with possibility of up to 2 year extension)

Dr Seth Coffelt

Cancer Research UK Beatson Institute in Glasgow is one of Europe's leading cancer research centres. It supports cutting edge research into the molecular mechanisms of cancer development. The Institute provides an outstanding research environment, underpinned by state-of-the-art core services and advanced technologies with special emphasis on imaging, metabolomics and in vivo models of cancer.

The Coffelt lab is seeking a highly motivated and creative individual to investigate how mammary tumours instruct IL-17- and IFNg-expressing γδ T cells to promote cancer spread. This work will follow on from our recently published data in Nature (see Coffelt et al. 2015). We offer a unique opportunity to combine metastasis biology with immunology in genetically engineered models of breast cancer. The project will rely on a multidisciplinary approach involving sophisticated in vivo models, murine engineering, immune cell manipulation, multi-colour flow cytometry and state-of-the-art imaging techniques.

You will have a PhD in a field relevant to immunology or cancer biology, a track record of first class science demonstrated by first author peer-reviewed scientific articles, and a demonstrable capability for independent thinking. Experience with in vivo models is desirable.

Informal enquiries may be emailed to Dr Coffelt at s.coffelt@beatson.gla.ac.uk

Postdoctoral Research Associate in Intestinal Fibroblast Subsets

Closing Date: 2017-09-18

Institution: University of Oxford
Closing Date: 2017-09-18
Location: Oxford, United Kingdom
Salary: £31,076 - £38,183
Term: 2 years
Keywords: Research

Postdoctoral Research Associate in Intestinal Fibroblast Subsets

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, Old Road Campus, Oxford

Grade 7: £31,076 - £38,183 p.a.

We are seeking a Postdoctoral Research Scientist to join Professor Powrie’s Mucosal Immunology Group. You will join a dynamic and successful group studying immune regulation in the intestine and how this breaks down in inflammatory bowel disease and colorectal cancer. As a Roche Postdoctoral Fellow (RPF), you will be dedicated to a multi-centre project that investigates fibroblast diversity across different tissues. In collaboration with Roche diagnostics, Harvard University and the University of Birmingham, you will be responsible for the characterisation of intestinal fibroblast subsets in healthy individuals and patients with inflammatory bowel disease.

You will be an enthusiastic, motivated, highly organised scientist possessing knowledge and good practical experience in Immunology, cell culture and flow cytometry with an ability to produce work to a high standard. A PhD in immunology or related sciences together with a desire to undertake cutting-edge scientific research is essential. Excellent communication skills with the ability to present results clearly and logically, working co-operatively as part of a team as well as independently, are also essential capabilities for this post. Experience of working with inflammatory bowel disease samples or next-generation sequencing and data analysis would be an advantage.

This is a full-time position, fixed-term for 2 years, funded by Roche.

You will be required to upload a CV and a supporting statement as part of your online application

The closing date for applications is 12.00 noon on Monday 18 September 2017.

Please note that the University of Oxford's retirement policy is changing. With effect from 1 October 2017, all employees at Grade 8 and above will have a retirement age of 68, and all employees at Grades 6 and 7 will no longer have a set retirement age. Further details are available here: https://www.ox.ac.uk/about/jobs/preemploymentscreening.

Contact Person : Recruitment Team Vacancy ID : 129786 Contact Phone : 01865 737843 Closing Date : 18-Sep-2017 Contact Email : personnel@ndorms.ox.ac.uk

Advanced Research Assistant

Closing Date: 2017-08-30

Institution: Wellcome Trust Sanger Institute
Closing Date: 2017-08-30
Location: Cambridge, United Kingdom
Salary: £24,589 to £30,995 pa
Term: 3 years
Keywords: Research

Advanced Research Assistant: Genetic Screens in Dementia

An Advanced Research Assistant position is available in Rick Livesey’s group at the Wellcome Trust/Cancer Research UK Gurdon Institute, as part of a translational initiative led by the Wellcome Trust Sanger Institute called Open Targets (https://www.opentargets.org). This is a collaborative project between Dr Rick Livesey, Dr Ludovic Vallier (Wellcome Trust Sanger Institute; WTSI) and Dr Heike Hering (Biogen).

The successful candidate will be based in the centre of Cambridge at the Gurdon Institute, where they will contribute to the optimisation and execution of robust CRISPR – Cas9 based screening assays to identify targets that modulate a key process in the progression of Alzheimer’s disease using neurons induced from human pluripotent stem cells (IPSC). We welcome candidates with a background in cell biology, molecular biology and/or neurobiology with experience in performing cell and molecular biological assays. Experience in mammalian cell culture and flow cytometry are desirable, as is a background with handling human IPSC.

Essential Skills

  • Graduate qualification in Biological Sciences, or equivalent qualification.
  • Experience of core molecular and cell biology techniques.
  • Experience with flow cytometry and mammalian cell culture.
  • Excellent organisational, communication skills and work ethic. 
  • Ability to independently develop, optimise and deploy research support, as a member of a closely collaborative team.
  • Ability to work both as part of a team and also independently once appropriate training and guidance have been provided.
  • Good communication skills to allow accurate information to be exchanged
  • Good computer skills in the use of office software (e.g. Excel, Word, Powerpoint) 

Ideal Skills

  • Experience with CRISPR-Cas genome engineering
  • A background in neurobiology, especially Alzheimer’s disease research
  • Experience in handling human induced pluripotent stem cells
  • Experience of high-throughput genomics.

Other information

Open Targets is a recently established pioneering public-private initiative between GlaxoSmithKline, Biogen, EMBL-EBI (European Bioinformatics Institute) and the WTSI. Open Targets aims to generate evidence on the biological validity of therapeutic targets and provide an initial assessment of the likely effectiveness of pharmacological intervention on these targets, using genome-scale experiments and analysis. The goal of the platform is to apply the latest innovations in systems biology and genome sequencing to improve the success rate for discovering new medicines and share its data openly with the scientific community in the interests of accelerating drug discovery.

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application.  

Closing date for applications: 30th August 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.

Selected candidates will be contacted for interview and references by the 31st of August. The interview date is fixed and will take place on the 5th of September.

Research Assistant/Associate

Closing Date: 2017-09-06

Institution: University of Newcastle
Closing Date: 2017-09-06
Location: Newcastle upon Tyne, United Kingdom
Salary: £26,829 - £38,183
Term: 12 months
Keywords: Research

A79787R (NICR) Research Assistant/Associate

Northern Institute for Cancer Research, Newcastle upon Tyne

Research Assistant (PhD not awarded) £26,829 - £28,452
Research Associate (PhD awarded) £29,301 - £38,183

Please be advised that due to a new minimum salary threshold of £30,000 per annum imposed by the UKVI, this post may not qualify for University sponsorship under Tier 2 of the points based system.

Based in the laboratory of Professor James Allan within in the Northern Institute for Cancer Research, Newcastle University, a Bloodwise-funded post you will work on projects investigating the molecular genetics of acute myeloid leukaemia, including aetiology, prognostication and the development of novel therapies.

You will have an undergraduate degree in a relevant science subject, preferably biological/biomedical and a PhD in the area of biomedical sciences, cancer research, molecular biology or cell biology for appointment at associate level. You will have expertise in contemporary molecular and cell biology techniques (Western blotting, real-time PCR, cloning), cell culture, flow cytometry, lentiviral transduction and in vivo models (with appropriate approvals).

You will have experience of presenting work at scientific meetings and able to demonstrate capacity for original thought, in addition to having excellent communication and team-working skills.

The position is available from October 1st 2017 for 12 months.

Informal enquiries should be made to Professor James Allan (james.allan@newcastle.ac.uk).

Information about the Institute can be found at: http://www.ncl.ac.uk/nicr/

Information about the Adult Cancer group can be found at http://www.ncl.ac.uk/nicr/research/adult-cancer/

Faculty of Medical Sciences

Biomedical Scientist

Closing Date: 2017-09-04

Institution: Royal Derby Hospital
Closing Date: 2017-09-04
Location: Derby, United Kingdom
Salary: £22,128 - £ 28,746 pro rata pa
Term: Permanent
Keywords: Technical Clinical

Biomedical Scientist - Band 5

Are you looking for a new challenge?

There has never been a better time to come and work at Derby Teaching Hospitals NHS Foundation Trust; we are a leading Teaching Hospital with care, safety, compassion and pride at the heart of our organisation.

With over 8,500 members of staff you can expect huge variety and new opportunities every day! Our staff go above and beyond and are taking pride in caring for our patients – making every moment matter.

Think you’ve got what it takes to join us?

Here’s more about the role and what we’re looking for; 

We are inviting applications from experienced, motivated and enthusiastic candidates to join our friendly and hard working team in Blood Sciences. You will receive appropriate induction and training after which you will be expected to participate in the 24/7 shift rota, once appropriate competencies have been completed. There are posts available in the Haematology/Blood Transfusion and Biochemistry areas and if candidates have a preference for which discipline they prefer, this should be stated on application.

Ideally candidates will be HCPC registered or have evidence of working towards their IBMS Registration Portfolio. However this post may also be suitable for First or Second class Biomedical Science graduates who wish to begin working towards their HCPC registration.

We have a modern laboratory which is well equipped. In Haematology we currently have tracked Sysmex FBC analysers, Vescube ESRs, Sysmex coagulation, Beckman Coulter Flow Cytometry, Biorad Variant HbA1c analysers and Biorad IH1000's in Blood Bank. In Biochemistry we have tracked Roche Cobas 8000 and 6000 analysers, Sebia electrophoresis, Phadia Immunocap 250, HPLC and Tandem Mass Spectrometry.
We are fully accredited with CPA and have full training status with the HCPC. CPD is encouraged and supported.

This is an opportunity to join a friendly well motivated team and we would encourage you to contact us to discuss the post further or to arrange an informal visit.

We are a fantastic Trust and want the very best skilled people to work with us to provide excellent patient care.

Join the conversation and follow us on social media…

Follow us on Twitter @DerbyHospitals or find us on Facebook & LinkedIn - Derby Teaching Hospitals

If you wish to apply for this post, please click apply and complete your application.

Please note we will communicate any interview arrangements with you via email so please check your email account on a regular basis after submitting your application.

Most of our posts are subject to a DBS check, however having a criminal record will not necessarily bar you from obtaining a position. Please be aware that all new employees starting work with us will be charged for the cost of their DBS check, if it is required for their role. The cost will be deducted from pay.

Applicant requirements

You must have appropriate UK professional registration.

Documents to download

To print a document or save it to your computer, please click with your right mouse button on the document title and select "Save Target As...". You can then save the document in a suitable place on your computer ready to print it out. Clicking with the left mouse button will open the document in a new window (if your web browser can do so).

Locum Consultant in Haematology

Closing Date: 2017-09-07

Institution: John Radcliffe Hospital
Closing Date: 2017-09-07
Location: Oxford, United Kingdom
Salary: £76,761 to £103,490 pa
Term: Fixed Term
Keywords: Clinical

Locum Consultant in Haematology

John Radcliffe Hospital, Oxford, UK

The Oxford University Hospitals NHS Trust is one of the largest NHS teaching trusts in the country. It provides a wide range of general and specialist clinical services and is a base for medical education, training and research.

The Trust comprises of four hospitals - the John Radcliffe Hospital, Churchill Hospital and Nuffield Orthopaedic Centre in Headington and the Horton Hospital in Banbury.

Our values, standards and behaviours define the quality of clinical care we offer and the professional relationships we make with our patients, colleagues and the wider community. We call this Delivering Compassionate Excellence and its focus is on our values of compassion, respect, learning, delivery, improvement and excellence. These values put patients at the heart of what we do and underpin the quality healthcare we would like for ourselves or a member of our family. Watch how we set out to deliver compassionate excellence via the OUH YouTube channel.

Many of our recruitment programmes use values-based interviewing to identify those who have the skills we seek, who share our values and who are able to deliver compassionate excellence from the outset. We know that this makes a significance difference to your job satisfaction and above all the outcomes and experience of our patients and their families.

For more information about our Values and Value Based Interviewing please visit  http://www.ouh.nhs.uk/about/vision-and-values/default.aspx

OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST

HAEMATOLOGY LOCUM CONSULTANT (Malignancy)

Applications are invited to apply for the above post that will be based primarily in laboratory haematology at the John Radcliffe Hospital.

A new opportunity has arisen to appoint a full-time NHS locum consultant to support and further develop the Oxford haematology diagnostic laboratory, to provide consultative haematology support on the John Radcliffe Hospital site.

The successful candidate will have the opportunity to develop a special interest in flow cytometry and integrated reporting for diagnosis of haematological malignancies.
This post forms part of a team of consultants developing and providing a first class, modern, integrated laboratory haematology service, and aims to forge closer links between the clinical haematology service and laboratory services.

No unsolicited recruitment agency telephone calls or emails.

Please make sure that you read the job description and person specification attached below, and that your statement in support reflects this as your application will be judged against these criteria.

All candidates will be contacted with an update on the application. The majority of correspondence will be via the e-recruitment system, therefore you should check your emails regularly including junk mail folders in web-based email products.

Applicant requirements

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service.

Documents to download

To print a document or save it to your computer, please click with your right mouse button on the document title and select "Save Target As...". You can then save the document in a suitable place on your computer ready to print it out. Clicking with the left mouse button will open the document in a new window (if your web browser can do so).

Research Assistant in Myeloid Neoplasias

Closing Date: 2017-08-30

Institution: University of Oxford
Closing Date: 2017-08-30
Location: Oxford, United Kingdom
Salary: £27,629 - £32,958 p.a.
Term: 12 months
Keywords: Research

Research Assistant in Myeloid Neoplasias

Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford

We are seeking a motivated and enthusiastic Research Assistant to work on a joint project between the laboratories of Professor Claus Nerlov and Professor Paresh Vyas on genetic modelling of myeloid malignancies.

The MRC Weatherall Institute of Molecular Medicine is a research institute undertaking research into the processes underlying normal cell and molecular biology and its aim is to determine the mechanisms by which these processes are perturbed in inherited and acquired human diseases. The Molecular Heamatology Unit is a world-leading centre of research into the causes and treatment of blood disorders, and myeloid malignancies in particular. The postholder will be responsible for generation and analysis of genetically accurate models of acute myeloid leukaemia and myeloproliferative disorders, using state-of-the-art genetic and functional genomics approaches, including CRISPR-Cas9–based genome engineering and single cell transcriptome analysis.

Candidates will hold a degree in a biomedical related area and have previous experience in the field of hematopoiesis, preferably including work on myeloid malignancies, and will be proficient in genetic, molecular biology and flow cytometry techniques. Experience with bioinformatics would be desirable. The ability to work as a team member and independently together with excellent organisation and communication skills are essential to the post. Most importantly, the postholder will have a high level of commitment to work and a true passion for furthering scientific research.

The post is available fixed-term for 12 months, funded by the Oxford Biomedical Research Centre (BRC) and departmental funds.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The closing date for this position is 12.00 midday on Wednesday 30 August 2017.

Contact Person: HR Manager

Vacancy ID: 130142

Contact Phone : 01865 222453

Contact Email: recruitment@imm.ox.ac.uk

Research Associate

Closing Date: 2017-09-10

Institution: University of Cambridge
Closing Date: 2017-09-10
Location: Cambridge, United Kingdom
Salary: £30,175 to £38,183
Term: 3 years in first instance
Keywords: Research

Research Associate (Fixed Term)

The Halim lab is actively recruiting highly talented and motivated scientists to join a recently established tumour immunology group within the CRUK Cambridge Institute. We are interested in understanding the role of innate lymphoid cells in regulating the immune response to cancer. Our long-term goal is to pharmacologically modulate the function of innate lymphoid cells to polarize the local immune environment towards an anti-cancer phenotype.

As a postdoctoral researcher in the group, you will drive your research project and establish novel in vivo and in vitro models to assess the function of immune cells in cancer as well as study signalling pathways and downstream mechanisms using cutting edge genomic and proteomics approaches.

Candidates must have experience in animal (mouse) experimental procedures, isolation and phenotyping of cell subsets using flow cytometry, gene expression analysis, IF microscopy, and molecular biology. Ideally you have demonstrated creative and independent work in your area of expertise. A strong background in molecular biology will be valued.

Applicants who wish to be considered must display the ability to undertake project management, method development, data collection and analysis. You must have excellent communication and organizational skills, the ability to develop innovative experimental approaches to answer research questions, and thrive both in independent research and while working collaboratively as part of a team.

The successful candidate must have (or be about to receive) a PhD (or equivalent) in immunology and will be appointed as a grade 7 (£30,175-£38,183) dependent on experience.

About Cancer Research UK, Cambridge Institute Europe's top cancer charity, Cancer Research UK, has teamed with the University of Cambridge to create the world class Cambridge Institute (CI) situated on the Addenbrooke's Biomedical Campus in Cambridge.

The Institute's research ranges from basic cancer biology through translational research to clinical application. The Institute currently houses over 350 researchers and contains new state-of-the-art research facilities. (http://www.cruk.cam.ac.uk/).

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

The closing date for applications is 10 September 2017. Interview dates are to be confirmed. If you have any questions about this vacancy or the application process, please contact Mailbox-hr@cruk.cam.ac.uk

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference SW13040 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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