Research Technician - Immunology and Immunotherapy

Job Details
Institution: University of Birmingham
Term: ntil 31st December 2019
Keyword Names: Academic/Research
Salary: £22,722 to £24,411
Line 1: University of Birmingham
City: Birmingham
Country: United Kingdom

Job Description

Research Technician - Immunology and Immunotherapy

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK

Job Purpose

We have funding to support a research technician SB500 through an MRC project grant MR/P001874/1, “Determining the potential universal applicability of a diurnal response to vaccination and the associated circadian immune processes” The technician will support the project by being involved in animal experiments and laboratory analyses, analysing immune cell activation using flow cytometry, real time PCR, fluorescence microscopy and ELISA.

Main duties

Research – 75%
The candidate will support a MRC project grant to Janet Lord and Kai-Michael Toellner on the regulation of diurnal variation of the vaccine response in mice and will work directly with KMT and be embedded in his lab group in the UoB Medical School Institute of Biomedical Research.

The candidate will analyse B cell responses to vaccination in mice:

  • Prepare antigens to immunize mice
  • Dissect animals and sample tissues and blood
  • Analyse antibody titres using ELISA
  • Analyse the cellular immune response using immunohistology and fluorescence microscopy, prepare stained cell suspensions for flow cytometry and sorting, and analyse gene expression using real time PCR
  • Experimental data will be recorded and analysed

The technician will already be proficient in these techniques, or will be able to use and apply these techniques independently after being trained by experienced members of the lab. 

This knowledge is to be gained from extensive practical experience and formal qualifications.

The technical and/or other skills will vary according to the work area and support the requirements of research group(s) working within the area. However it is expected that all appropriate/required knowledge/skill base will be delivered at the “higher level” and include but are not restricted/limited to the following:

  • Safe working practices
  • Working to deadlines and providing consistent results delivery
  • Resolving problems that may affect the achievement of objectives and deadlines
  • Communicating results to colleagues
  • Providing support and guidance to junior members of staff and/or students
  • Maintaining good record keeping
  • An awareness of University & Trust Health & Safety policies and procedures (if applicable)