|Institution:||Amsterdam University Medical Center|
|Line 1:||Amsterdam UMC|
Translational research with state-of-the-art biomedical and cellular techniques.
What will you do
Within the department of Molecular Cell Biology and Immunology at Amsterdam UMC, location VUmc, our group studies the glyco-code in cancer as novel checkpoint inhibition to discover new inhibitory pathways in the tumor microenvironment. This project incorporates fundamental research questions in the analysis of patient material with the ultimate goal to incorporate new diagnostics and treatments into the clinic.
The successful candidate will study glyco-profiles in the tumor microenvironment of lung cancer patients and will address the biological importance of these signatures in patients’ biopsies and in vitro human models.
Your main tasks and responsibilities are:
What do we expect
We are looking for a highly motivated and enthusiastic researcher with:
Your working environment
You will work in a team with young and enthusiastic researchers, who have expertise in glyco-immunology, biochemistry, cell biology and cancer. You will form a bridge with the clinical department of Pulmonary Disease with whom this projects is performed. Research is embedded in the Cancer Immunology program of the research institutes Cancer Center Amsterdam (CCA) and Amsterdam Immunity and Infection Institute (AI&II).
Research within the department of Molecular Cell Biology and Immunology is performed in a vibrant and international high competitive level environment within the O|2 Lab Building , located near the hospital. The department consists of several research groups that study immunological processes at cellular and molecular level in health and disease.
The research group 'Dendritc cell immunobiology' focusses on posttranslational modifications in the tumor microenvironment such as glycosylation that initiates novel immune suppressive pathways. Our goal is to discover new targets for treatment and biomarkers for diagnosis. We also develop new cancer vaccines that are aimed to reboot the cancer patient’s immune system. Current work is focussed on glioblastoma, melanoma and pancreatic cancer. For a new research line that focuses on lung cancer and breast cancer we seek new group members. This work is performed in close collaboration with clinical departments of Pulmonary Diseases and Medical Oncology at Amsterdam UMC.