Postdoc perivascular single cell transcriptomics

Job Details
Closing Date: 2019-08-24
Institution: Ludwig- Maximilians-University (LMU)
Keyword Names: Academic/Research
Address
Line 1: Ludwig- Maximilians-University (LMU)
City: Munich
Country: Germany

Job Description

Postdoc perivascular single cell transcriptomics

Institute for Cardiovascular Prevention, Ludwig- Maximilians-University (LMU), Munich, Germany

The Ludwig- Maximilians-University  (LMU) in Munich, Germany, is recognized as one of Europe's premier academic and research institutions. In the Times Higher Education (THE) World Reputation Ranking 2019, LMU is ranked 43rd and represents Germany’s most highly regarded university. As part of the German federal and state governments’ Excellence Strategy, LMU has been awarded funding as University of Excellence. Hence, the LMU is particularly noted for providing excellent conditions for innovative research.

The Institute of Cardiovascular Prevention, Ludwig-Maximilians-University in Munich is looking for a Postdoctoral Researcher (f/m/d)

Perivascular single cell transcriptomics (Ref 2019_07_postdoc)

The laboratory of Prof. Dr. Sabine Steffens studies 

  • inflammatory processes underlying cardiovascular disease, in particular atherosclerosis and myocardial infarction
  • endogenous lipid signalling receptors which regulate immune cell function in this pathophysiological condition

Brief description about the project:

The aim is to study the immune cell diversity of the pericardial adipose tissue during homeostasis and in response to cardiac injury. The postdoc shall perform a detailed single-cell analysis of murine and human cardiac adipose tissue. Complementary analysis involves imaging of pericardial fat lymphoid clusters and flow cytometry-based immunophenotyping of pericardial immune cells. Our international and interdisciplinary team is part of larger research consortia, in particular the DFG-funded CRC1123 and German Center for Cardiovascular Research (DZHK). 

We offer a full-time appointment (TVöD E13), which initially is limited to two years with the possibility of extension.

The applicant should be able to develop methods in the single-cell RNA sequencing and imaging.

You have a PhD in Biology, Biochemistry or a related field and experience in transcriptomics documented by publications. We expect solid knowledge in statistics and data processing of RNA seq data. Experience with (cardiovascular) mouse models, flow cytometry and bioimaging techniques would be an additional advantage. 

You are creative, highly motivated and you can work independently. Essential qualities include good organizational skills, fluency in English, a strong team spirit, and time management skills.

Interested candidates should submit their application (including CV, publication list and references as single PDF) via email to: sabine.steffens@med.uni-muenchen.de