Research Fellow (Sir Jules Thorn Award)

Job Details
Closing Date: 2019-04-24
Institution: University of Birmingham
Term: 5 years
Keyword Names: Academic/Research
Salary: £30,395 to £39,609
Line 1: University of Birmingham
City: Birmingham
Country: United Kingdom

Job Description

Research Fellow (Sir Jules Thorn Award)

University of Birmingham, Birmingham, UK

Additional Information - Dr Ye Oo (

Job Purpose

We are looking for a enthusiastic and skilled post-doctoral research fellow to actively participate and contribute to this exciting programme of bench to bedside delivery of regulatory T cell therapy delivery in autoimmune liver disease with Sir Jules Thorn Award.

  • To deliver Sir Jules Thorn Trust Award research grant remit and its related research programme and contribute to writing manuscripts, delivering immunological studies for clinical trials and writing research bids;
  • Operate within area of autoimmune liver disease;
  • Immunological cell cultures, gene analysis, developing new methodology related to the programme of research;
  • Overseas learning of methodology to deliver research programme (the candidate will be expected to work abroad for a short period);
  • Experience with TCR/BCR repertoire analysis, CyTOF is desirable;
  • GCP certificate and understanding of GCP is desirable;
  • Analyse and interpret research findings and results

The programme of research is both basic science and early phase translational regulatory T cell therapy trial delivery from prestigious Sir Jules Thorn Award.

The job will involve working in a multidisciplinary team with clinicians, research nurses (from Birmingham BRC), clinical research fellows, cell therapy team, other post-doctoral scientists, research technician and PhD students/intercalated medical students.

Flexibility of working time is crucial as majority of work evolve around clinical samples (blood and tissue). Great communication skills is an essential component as the programme of research involve multiple collaborators in UK and abroad.

The responsibilities may include some but not all of the responsibilities outlined below.

  • To deliver the research programme in autoimmune liver diseases supervised by PI;
  • Develop research objectives and proposals for own or joint research, with assistance of a mentor if required;
  • Contribute to writing bids for research funding;
  • Analyse and interpret data;
  • Apply knowledge in a way which develops new intellectual understanding;
  • Disseminate research findings for high impact publications, research seminars etc;
  • Collaborate actively both nationally and globally related to autoimmune research programme;
  • Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline;
  • Contribute to developing new models such as liver machine perfusion, techniques and methods;
  • Undertake management/administration arising from research
  • Contribute to Centre of Liver and Gastro Departmental/Institute of Immunology and Immunotherapy research-related activities and research-related administration
  • Contribute to enterprise, business development and/or public engagement activities of manifest benefit to the College and the University, often under supervision of a project leader
  • Collect research data; this may be through a variety of research methods, such as scientific experimentation, literature reviews, and research interviews
  • Present research outputs, including drafting academic publications or parts thereof, for example at British liver meeting (BASL), European Liver Meeting (EASL), American Liver Meeting (AASLD), BSI, ECI and Keystone meetings as seminars and as posters
  • Provide guidance, as required, to support staff and any students who may be assisting with the research
  • Deal with problems that may affect the achievement of research objectives and deadlines

Person Specification

  • PhD in Immunology and understanding/experience in autoimmunity or close to completion
  • Cell therapy experience is highly desirable
  • GCP certificate
  • Essential to have skills of great communicator and team player, leadership potential
  • Previous experience with CyTOF, 10X gene analysis, TCR/BCR repertoire analysis is highly desirable
  • High level analytical capability
  • Ability to communicate complex information clearly both in basic science and translational aspect
  • Competent in FACS, PCR, immunostaining, cell culture techniques, interpreting results and ability to Contribute to developing new ones
  • Developing new methodology such as machine perfusion
  • Ability to assess resource requirements in the group, purchase and use resources effectively
  • Understanding of and ability to contribute to broader management/administration process of Institute, Birmingham BRC and Centre for Liver and Gastroenterology Research.

Full job description is available in PDF format: