Research Associate II-Flow Cytometry

Job Details
Institution: Frederick National Laboratory
Keyword Names: Core/Shared Resource Laboratory, Technologist
Address
Line 1: Frederick National Laboratory
City: Frederick
State / County: MD
Country: United States

Job Description

Research Associate II-Flow Cytometry

Frederick National Laboratory, Frederick: Ft Detrick, USA

Position Overview:

PROGRAM DESCRIPTION

The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics.  Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR).  The Flow Cytometry Core (Flow Core) of the Cancer & Inflammation Program (CIP) is a service core which supports the research efforts of the CCR by providing expertise in the field of flow cytometry (using analyzers and sorters) with the goal of gaining a more thorough understanding of the biology of cancer and cancer cells.  The Flow Core provides service to 12-15 CIP laboratories and more than 22 non-CIP laboratories.  Flow core staff provide technical advice on the experimental design of applications, which include immunological phenotyping, cell function assays, and cell cycle analysis.  Work is performed per customer requirements,
and no independent research is involved.

KEY ROLES/RESPONSIBILITIES

  • Monitor performance of and maintain high dimensional flow cytometer analyzers and cell sorters
  • Operate high dimensional flow cytometer analyzers and cell sorters
  • Monitor lab supply levels and order lab supplies
  • Perform various record keeping responsibilities
  • Assist in the training of scientific end users on the use of flow cytometry in their research, as well as how to operate and troubleshoot the bench-top analyzer instruments
  • Experience with sterile technique and tissue culture
  • Requires analytical problem solving abilities
  • Complex assignments are performed independently and reported to supervisor or scientist
  • Must be able to function, and communicate, in a close team environment
  • May be required to develop new assays or production methods
  • May supervise a staff of technical personnel
  • May initiate a research project by setting up a laboratory
  • Responsible for data triage and quality control evaluations
  • Responsible for maintaining essential laboratory supplies and equipment
  • Serves as technical authority in the absence of the lead laboratory scientist
  • Independently performs assay methods development and validates the reliability of the methodology
  • May include formal reporting of data including presentation and/or publications
  • Performs other related duties as assigned by a responsible authority. Function independently in a laboratory of research or specialized scientific service, requiring originality and judgement
  • Independently evaluate the suitability and quality control of research or production assays or tests; supervise a technical staff. Basic subject matter of specialty area (i.e., biochemistry, immunology, cell biology, etc.); advanced data reporting techniques, mathematics and statistics
  • Basic laboratory techniques germane to the specialty area (i.e. sterile procedures, safety procedures, instrument operation, etc.)

BASIC QUALIFICATIONS

  • Possession of an Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a related field (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency.
  • In addition to educational requirements, a minimum of five (5) years related biomedical experience
  • Basic understanding of flow cytometry principles and multiparametric instrumentation
  • Must be able to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

  • Previous work experience in a fluorescence cell sorting
  • Experience with BD flow cytometers and DIVA software